Candle
A proteasome-associated autoinflammatory syndrome that is characterized by early childhood onset of annular erythematous plaques on the face and extremities with subsequent development of partial lipodystrophy and laboratory evidence of immune dysregulation and that has_material_basis_in homozygous or compound heterozygous mutation in the PSMB8 gene on chromosome 6p21. Digenic forms of PRAAS1 can be caused by heterozygous mutation in the PSMB8 gene and heterozygous mutation in either the PSMA3 gene on chromosome 14q23 or in the PSMB4 on chromosome 1q21.
The label is preserved as historical source vocabulary and may not map cleanly to current terminology.
The plain-language definition is anchored to an exact Disease Ontology term. The historical use association remains a separate data claim.
Recipes, methods and preparation notes.
The historical dataset does not contain a recipe. A preparation will appear here only when the editorial library contains a separately sourced note connected by plant identity or explicit use language.
Browse curated preparations ↗Agrostis lachnantha
Where the association appears.
View 1 preserved source rows
Multiple rows can represent different places, references or repeated historical reports. They are preserved separately rather than treated as independent proof.
| Region | Reference label | Source row |
|---|---|---|
| Lesotho | Guillarmod | #9,939 |
Safety and self-care boundary
Use this page as a research index. Persistent, severe, unexplained or worsening symptoms need appropriate clinical assessment.
Plant identity, plant part, dose, preparation, route, interactions, pregnancy safety, toxicity and contraindications are not established by this association. Do not use it for self-diagnosis or self-medication.
USDA Dr. Duke ethnobotanical data
The plant–use association and source rows come from the USDA Dr. Duke database. Holistic Healing Tips adds taxonomy matching, readable vocabulary profiles, internal preparation links and visible interpretation boundaries.
Dataset version: 1992–2016 · Licence: CC0 · Record class: traditional use
Read the data methodology ↗